Pharma Tips

Amlodipine Besylate

By: Pharma Tips | Views: 4283 | Date: 17-Jul-2011

Amlodipine besylate is an orally administered drug, used for treating hypertension and angina pectoris. It has a long duration action for treating them. This calcium channel blocker is available in tablet form. The tablets are available in varying potencies of 5mg and 10 mg depending on the severity of the individual case. It is a prescription drug and is not available over the counter.

Amlodipine besylate is an orally administered drug, used for treating hypertension and angina pectoris. It has a long duration action for treating them. This calcium channel blocker is available in tablet form. The tablets are available in varying potencies of 5mg and 10 mg depending on the severity of the individual case. It is a prescription drug and is not available over the counter.


Brand Names of Amlodipine Besylate
Azor (combination), Exforge (combination), Caduet, Lotrel, Norvasc

Chemical Description
3-Ethyl-5-methyl (±)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate, mono-benzenesulphonate.


Uses of Amlodipine Besylate
Amlodipine Besylateis used in the treatment of hypertension, and coronary artery disease. The drug is used alone or in combination with other classes of antihypertensive agents. It can be used in fixed combination with olmesartan, benazepril, or valsartan when such combined therapy is indicated.


Working of Amlodipine Besylate
The drug inhibits the trans membrane influx of calcium ions into the cardiac muscle and smooth muscle. It is very useful for treating chronic, stable and vasospastic angina. The drug works by blocking the calcium needed for muscle contraction and works primarily on the arterial muscle. The effect of this drug is to relax the arterial muscles, leading to their dilation and finally a drop in the blood pressure within them.


Dosage:
5 to 10 mg once a day

Side Effects of Amlodipine Besylate
The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug:
Headache
Fatigue
Dizziness
Flushing
Palpitation
Nausea
The drug should not be given to pregnant and lactating women, the dosage of the drug should be reduced when given to elderly. The side effects of the drug mentioned above may or may not occur in individuals.

 

Disclaimer: The above information is for general understanding of the visitor. Please consult a registered medical practitioner before taking the aforesaid medicine.

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